Sentence examples for affinity suffices from inspiring English sources
These findings clearly show that no long-range interactions are necessary for forcing the polymer to collapse but a purely diffusional motion together with chromatin-chromatin binding affinity suffices to achieve this.
In this system, knowledge of the fibrillation kinetics and inhibitor affinities suffices to predict the effect of kinetic inhibitors on fibrillation lag times.
Thus, negatively charged lipids appear to be required for finite binding and it is possible that only one or a few PI molecules, preferentially PI(3 P, suffice for significantly increasing affinity and, thereby, specificity of SUMO binding to lipid membranes.
While NK cells and macrophages share some common Fc-receptors, it understates the complexity of immunotherapeutic approaches to assume that a generic approach of increasing antibody affinity for activatory receptors will necessarily suffice for achieving optimal effector cell engagement.
Other issues concern the specificity, affinity (affinities sufficient for therapy may not suffice for imaging) and size of tracer molecules (large molecules are retained in blood and have a lower diffusion capacity, resulting in low target-to-background ratios).
This research demonstrates that a single Nanobody target binding domain suffices and confers equal or higher affinity binding compared to published data of therapeutic monoclonal antibodies, where bivalent binding is conferred by four domains [ 24].
First, the origin of such a function does not require the establishment of a complex structure ab initio; only a moderate binding affinity of RNA or a short peptide would suffice to provide the starting point for evolutionary selection.
An attractive hypothesis was that Tyr1022Cys shifts GeaA1 localization towards the late Golgi, perhaps by reducing its affinity for an early Golgi receptor, and that this suffices to bypass HypB partially.
However, as both APRIL and BAFF share nanomolar affinity for TACI, one could speculate that the elimination of only BAFF and not APRIL might not suffice in inhibiting NF-κB activation.
