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The phrase "affinity problem" is correct and usable in written English.
It can be used in contexts related to chemistry, biology, or social sciences, where it refers to issues related to attraction or connection between entities.
Example: "The researchers encountered an affinity problem when trying to determine the binding interactions between the two molecules."
Alternatives: "attraction issue" or "connection challenge".
Exact(2)
In the case of differentially expressed regions, probe-artefacts should be equivalent in both conditions and hence regions detected as differentially expressed should be trusted, although there might be uncertainties connected to the absolute signal intensity values, due to the probe affinity problem.
The PPI affinity problem involves finding a protein pair that is interactive from a protein group with a known structure.
Similar(58)
Our solution to the affinity reagent problem is to develop a new class of affinity reagents that can be developed in a high-throughput manner using minimal amounts of protein.
Use of PNAs was limited by lack of affinity, a problem which has been recently overcome by introduction of negative charges to enhance binding [ 4– 8].
The Chelsea Society has been closely involved, and is sympathetic to Affinity's problems.
Our results were not in agreement with the common beliefs that people with poorer levels of education might show stronger affinity for problem-prone behavior and are therefore expected to use drugs of abuse [ 35].
To prove his grasp and affinity with the problem, Mr. Georgescu describes his childhood in labor camp, his separation from his parents, the surrounding uneducated working class, and his struggle to hoist himself from their unassuming origins to the high perches of power and money.
However, long probes pose a problem since affinity and specificity for nucleic acid probes usually are inversely correlated, meaning that whilst a probe's affinity for a target increases so does the risk of non-specific binding [ 7].
Such relationships need not be based on a mutual understanding of disciplines, but on a mutual affinity for solving the problem at hand.
To solve this problem, the affinity propagation clustering creates the centers and the corresponding clusters based on the constant exchanging of reading similarities between the RPs [19].
A general problem in affinity proteomics is distinguishing specific interactors from contaminants.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com