Sentence examples for affinity population from inspiring English sources

This indicates that there are at least two, maybe more, interactions occurring simultaneously, and it is in line with the description of a low affinity and a high affinity population of EGFRs [2].

The higher affinity class is characterised by a Kd of 100 p M and the lower affinity population by a Kd of 1200 p M. The addition of 0.3  μ M (IC50) NaPaC did not significantly affect the affinity of the first class sites, but induced the disappearance of the low-affinity population.

The higher affinity class is characterised by a Kd of 355 p M and the lower affinity population by a Kd of 1000 p M. The addition of 0.2  μ M of NaPaC (IC50) did not significantly affect the affinity of the first class sites, but induced the disappearance of the low-affinity population (data not shown).

The equilibrium dissociation constant (KD) for the high-affinity population (measured using cell-based real-time measurements and interaction analysis) was approximately 8 ± 2 nM and did not significantly differ between 125I- or 111In-labelled AbD15179 on the H314 or A431 cells [31].

While we would have liked to inhibit each form of the receptor independently, unfortunately there is currently no way to selectively perturb either the high- or low-affinity population of receptors, as they are both encoded by the same transcript.

Alternatively, the West Ligurian basins might have been colonized directly from the upper reaches of the Po system via river capture, as is indicated by the close genetic affinity of population 18 (river Orba) from the Po system to the geographically close populations of West Liguria (Figs. 1, 2).

It is shown that only MIPs having a binding isotherm with varying slope are suitable for the assay, but there is no need to interpret the isotherm in terms of site affinity and population.

Even when there is no cost of having high resource affinity, the population still fragments into approximately two stable lineages, but this is an effect of fixation by drift being a very slow process.

46 This study evolved around the cornerstone of 4 criteria of a good peptide epitope: good conservancy, T-cell and B-cell processivity, interaction with MHC-1 allele with good affinity, and population coverage.

The sequence of EP6b_B01 contained seven amino-acid substitutions from E09. Six of them were present in over 40% of variants in the affinity matured population at selection round six, and were thus classified as hot-spot mutations (Supplementary Figure 3).

Thus, the lack of a concordance between phylogeny and morphological or call divergence found here might then simply reflect a failure to accurately recover historical affinities among populations.