Sentence examples for affinity panel from inspiring English sources

Rpn13C was immobilized, whereas a gradient of Uch37 was applied to quantify the binding affinity (panel D).

Restriction to variable heavy chain gene IGHV1-69 in the high affinity mAb panel was associated with binding to a conserved hydrophobic pocket in the stem domain of HA.

Similar to a recent study, we found wild-type Parkin binds ubiquitinPhospho-Ser65 with a Kd of ∼156 nM affinity (left panel, Fig 3A and B) [ 19].

Developing a multi-target agent requires to monitor the affinity against a panel of similar targets.

This algorithm takes overlapping 9-mer frames derived from CHO protein sequences and scores them for potential binding affinity against a panel of class II HLA alleles; each frame-by-allele assessment that scores highly and is predicted to bind HLA is a putative T cell epitope.

Furthermore, it is incompatible with an undesirable unspecific, promiscuous mode of action of the compound [63]; II) affinities against a panel of human pathogens of the paramyxovirus family as well as laboratory adapted and wild type influenza virus isolates were very similar throughout (average EC50 concentrations are ∼40 nM).

Affinities at a panel of 5-HT receptors were determined by the NIMH-sponsored PDSP program (http://pdsp.med.unc.edu/kidb.php).unc.edu/kidb.php

The biological fingerprints composed either by binding affinities against a panel of proteins or by inhibition rates against a panel of cell lines and assays have been used to relate molecules.

The affinities of this panel of five scFv clones have been determined previously [ 12- 14], with a range of equilibrium dissociation constants (Kd) ranging from a lowest of 320 nM to the highest at 0.013 nM.

Recently, we have discovered 4 (BODIPY FL vinblastine) to be a potent PXR fluorescent probe and successfully used it in a TR-FRET assay to evaluate the PXR-binding affinities of a panel of putative PXR ligands: 1 (TO901317), 3 (SR12813), 5 (hyperforin), 6 (clotrimazole), 7 (rifampicin), 8 (ginkgolide A), and 9 (ginkgolide B).

Once these outliers were removed, the average reported affinity across the remaining panel of participants was 620 pM with a standard deviation of 980 pM.