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In particular the occurrence of NMS with medications with low D2 affinity has led to the proposal that sympathoadrenal hyperactivity resulting from the removal of tonic inhibition within the sympathetic nervous system may play an important role in NMS [ 13].
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The collapse of chemical diversity at the fragment level, combined with the need to use low-throughput biophysical assays to detect low-affinity binding, has led to small fragment libraries (1,000 10,000 compounds).
The ability of antibodies to bind an antigen with a high degree of affinity and specificity has led them to become the largest and fastest growing class of therapeutic proteins.
This systematic analysis of an agonistic antibody interacting with its receptor, in particular the exploration of the relationship between affinity and potency, has led to some surprising conclusions about the nature of agonistic antibody signalling.
The differential distribution and affinity of these receptors has led to the proposal that MRs maintain the tone of the stress system under normal conditions [ 155].
Although its dating is uncertain, the manuscript's affinity with the original scenario has led to speculation that the Udine version may have been compiled from the first performance.
His affinity for the grit of urban scenes has led to photographs of the Berlin Wall, New York and Paris.
These modifications has led to compounds with promising dual affinity and high MTs receptors agonist activity.
This, in turn, has led to many differing interpretations of its morphology and phylogenetic affinities.
Their fierce affinity with nature, and their aggression in its protection since the 15th century, when the tribe was founded, has led them to be thought of as the first environmentalists.
Leads from affinity precipitation have led to smart biocatalyst design which has inbuilt purification step.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com