The phrase "affinity gc" is correct and usable in written English, particularly in scientific or technical contexts.
It can be used when referring to affinity chromatography, a method used to separate and purify proteins or other biomolecules based on their specific interactions.
Example: "In our experiment, we utilized affinity gc to isolate the target protein from the complex mixture."
Alternatives: "affinity chromatography" or "affinity separation".
Low affinity GC receptors become additionally activated when GC levels are elevated, i.e., during wakefulness and stress (Born and Fehm, 1998; de Kloet et al., 1998, 2005; Joëls, 2008).
Gc1f-1f, tooughaveo have the highest affinity for 25OHD, had the highest 25OHD concentration compared with lower affinity Gc variants.
TFH cells facilitate the selection and maturation of high-affinity GC B cells by multiple rounds of cognate interaction with B cells in the light zone; these interactions provide the selected B cells with crucial signals for survival and re-entry into the dark zone3.
B cells with the highest affinity BCRs are able to outcompete lower affinity B cells for T-cell help, resulting in further clonal expansion of high-affinity GC B cells and formation of high-affinity plasma cells and memory B cells [ 14, 15].
Above the pzc, up to the bromide oxidation potential, MEM+ shows a much stronger chemical affinity to GC than MEP+ because the MEM morpholinium bridge oxygen shows a stronger interaction with the oxidised carbon surface species than the pure CH-structure of the pyrrolidinium species.
The combined results show that these acridone derivatives interact with DNA duplex by intercalation between the base pairs, possess higher affinity to GC than AT base pairs of the DNA and they could not interact noncovalently with the minor grooves of the DNA in solution-free gas phase.
GCs regulate hippocampal processes primarily via 2 nuclear receptors, the glucocorticoid receptor (GR), a ubiquitous transcription factor that mediates most GC-dependent transcription, and the mineralocorticoid receptor (MR), which has higher affinity for GCs and primarily mediates functions dependent on low corticosteroid concentrations (7, 21, 22).
This mutated protein would be expected to be deleterious, having reduced affinity for GC-box binding sites in promoter regions.
7-AAD is a red fluorescent, live-cell impairment chemical compound that intercalates in double-stranded DNA, with a high affinity for GC-rich regions.
The faster migrating bands were also observed when using nuclear extracts from non-transfected cells (Supplementary Figure 6B), suggesting the presence of other proteins with affinity for GC-rich sequences in these cells.
We further confirmed the apoptosis/necrosis-promoting effect of rVvhA by using another reagent that monitors the apoptotic cells with phosphatidylserine marker as well as the necrotic cells with 7-aminoactinomycin D (7-AAD), which has a strong affinity for GC-rich regions of DNA.
