Sentence examples for affinity engineering from inspiring English sources
Here we report a robust affinity engineering strategy using a custom designed library.
The method should facilitate affinity engineering of a wide variety of protein protein interactions due to its context-dependent library design strategy.
Our study on CXCL8 should pave the way for structure-based affinity engineering of the entire chemokine class.
To the best of our knowledge, the obtained value of 41 pM is amongst the best affinities obtained directly from any library panning, without the need for further affinity engineering.
In order to enhance their chemical affinity to engineering polymer matrices, chemical modification of the graphitic sidewalls and tips is necessary.
This system can therefore be used as a soluble expression platform downstream of a phage display library selection, or as an initial screen of a panel of native TCR clones to pick out the best starting point before stability or affinity maturation engineering.
Numerous examples of phage display applied to soluble proteins demonstrate the power of the technique for protein engineering, affinity reagent discovery and structure function studies.
Wheeler seriously considered medical school, but during her undergraduate days she developed an affinity for electronic engineering, which she felt she would have to give up if she became a physician.
We suggest that this simple approach is generally applicable as a tool to enhance binding affinity when re-engineering standard mechanism inhibitors.
