As stated earlier, proteins that are affiliated within a module are more likely to have similar functional properties [ 52].
The first GH12-affiliated module (F1_2; residues 539 to 747, 35.8% amino acid identity) is depicted in red and the second GH12-affiliated module (F1_3; residues 830 1089, 82.7% amino acid identity) is depicted in blue.
The finding of eight proteins with CBM48/GH13/CBM41 (pullulanases EC 3.2.1.41) modules affiliated with those from Klebsiella-like organisms (Table 2) pinpointed Klebsiella as the source organism for this specific activity.
For programs which participated in the 2008 2009 CKD module, affiliation with an affiliated nephrology fellowship training program was determined through the list of nephrology programs accredited by the Accreditation Council for Graduate Medical Education (ACGME).
Approximately half of the programs participating in the CKD module were affiliated with a renal fellowship training program, and approximately one-third of the programs were located in regions with the highest prevalence of ESKD in the U.S. Users of this CKD training tool have consistently rated it highly (4.4 out of 5).
Although the F1_2 and F1_3 modules are affiliated with the same class GH12, they are affiliated with two different independent clades (Fig. 4b).
Additionally, the contigs which were affiliated to diverse CAZyme modules (~13%), but could not be classified under any of the known or reported Pfam domains, indicated that the cattle rumen microbiome produces a large number of unique CAZymes which are meagerly characterized.
Each gene model cluster and affiliated peptides were also visualised using the BioPerl::Graphics module [ 32].
Two cellulase modules, F1_2 and F4_2_1, were identical and affiliated with an archaeal cellulase identified from Ignisphaera aggregans DSM 17,230.
We overlapped genes in the magenta cluster and those in the blue module and found 138 neuronal specific genes that were affiliated with neuronal maturation.
With this purpose in mind, a teaching/learning module was developed in this project at the KIST Medical College Nepal KISTMC (affiliated to TU) for teaching basic physical examination skills to second year students as part of early clinical exposure.
