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The structural difference between two splice isoforms markedly affects the specificity of ligand receptor binding [7], [8], [9], and exon switching is shown to be essential for development in the mouse [10], [11].
This factor mainly affects the specificity of the marker.
Limiting acetyl-CoA concentrations also affects the specificity of these proteins and also alters their order of specificity on H3 and H4.
Therefore, further studies should address how the sum of antibodies specific for these pathogens increases the risk to trigger a particular post infectious sequel and to which extent cross-reactivity of these antibodies affects the specificity of diagnostic tests.
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The conformation and lipidation status of apoE may affect the specificity of its receptor binding.
Third, false positives could be due to the cross-hybridization of paralogous gene targets to individual probes, which may affect the specificity of the SFP calling.
Moreover, markers can have limits in taxonomical assignments, mainly because of lack of consistent genome information from all possible species, affecting the specificity of the identification of the components [43].
The mechanism by which the upstream sequences affect the specificity of interaction remains unclear.
PBPs may also affect the specificity of the physiological response to sex phoromone.
These results suggest that, besides seed sequence, loop scores also affect the specificity of miRNA-mediated gene regulation.
However, phosphorylation in this region of p53 appears to be dispensable for the activation of some gene transcription by p53 [24], [24], although it may affect the specificity of interactions with other proteins.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com