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As shown in Table 1 the greatest increase in the rate of formation and decay of the TBP-TATA complex was observed for variant -35g (24-fold and 14-fold, respectively), which affects the sequence of the TATA-box and replaces its most conserved base "A" with "G" [ 122].
It should be noted that the variants -38a and -30t are located in the flanks of the TATAbox (the canonical form of a TBP-binding site), and only variant -35g affects the sequence of the TATAbox itself, thereby causing a massive decrease in affinity to 230 nM.
Of note is also the independent emergence of a tyrosine at position 363 in the fish PKR lineage and in XtPKR2 and OaPKR because it affects the sequence of the LFIQMEF motif that has been identified as important for eIF2α kinase activity [ 45].
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Also, the usage of specific song types (i.e. song categories) is related to different behavioral contexts or different times during the day and the breeding cycle, e.g. [ 39, 48– 52] which additionally affects the sequencing of songs.
"First, changing histones can change the activity of a gene without affecting the sequence of the DNA".
However, heating rate as an important processing parameter does not affect the sequence of these reactions.
Recently, it has been proved that another factor affecting the sequence of metals is the reactants concentration [18].
For example, a genetic code based on quadruplets could be artificially designed so that a single substitution of a single nucleotide in nearly any position of the template would not affect the sequence of the encoded protein.
One non-synonymous change affected the sequence of the APN1 AAEL012778 previously shown to bind Cry11Aa [ 46].
In addition to influencing the pathway organization, transposition and recombination of IS6100 elements can affect the sequence of Lin enzymes.
The authors concluded that "taste receptors seem to be able to partially affect the sequence of events during swallowing".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com