Sentence examples for affects the apoptotic from inspiring English sources

Retinal cells may have a different sensitivity to chromosomal instability, which affects the apoptotic pathways.

There are studies indicating that β-elemene affects the apoptotic process in cancer cells.

We also demonstrated that RUNX2 binds to and transactivates the Bcl-2 promoter, providing a mechanism for how RUNX2 affects the apoptotic potential of the cells.

Motivated by reports of a proapoptotic role for MKRN1 following DNA damage in the human osteosarcoma U2OS cell line 24, here we tested whether the manipulation of MKRN1 expression affects the apoptotic fate of ESCs undergoing ADR-induced genotoxic stress.

The number of apoptotic cells was moderately increased in the diabetic Wt but not in the diabetic Hif1a +/- hearts, which suggests that the Hif1a +/- genotype affects the apoptotic process in diabetic hearts.

Because TNF-α is involved in a variety of inflammatory and tissue repair processes, the question of how it affects the apoptotic response of potential target cells is of major interest.

While the initiation of apoptosis by the receptor complex and the execution via the mitochondrial pathway constitute two parts of the machinery, several other pathways affect the apoptotic process dramatically.

Similarly, we found that CD40 ligation neither promoted annexin-V binding in resting 1321N1 astrocytes (data not shown), nor co-incubation with erythrodiol or uvaol affected the apoptotic response elicited by triterpenes in these cells.

On the other hand, mutations affecting the apoptotic pathway have been found in a number of tumours.

In addition, Noxa levels affected the apoptotic response to general nutrient depletion (i.e. amino acids, vitamins).

Inhibition of actomyosin contraction through ROCK or myosin ATPase blockade reduces apoptotic body numbers formed during early apoptosis and concomitantly represses protein release without affecting the apoptotic program.