The phrase "affects on the expression" is not correct in written English.
The correct form would be "effects on the expression."
Example: "The study aimed to investigate the effects on the expression of certain genes in response to environmental changes."
Alternatives: "impact on the expression" or "influence on the expression."
The ACGT was placed in one or two copies and separated by different spacer lengths between the two copies, to study their affect on the expression of basal promoter in plant cells.
Another fundamental difficulty in identifying protein interaction subnetworks using expression data is inclusion of genes that are not significantly affected on the expression level, but are required for subnetwork connectivity.
Investigations are ongoing in our laboratory to determine if mixed tocopherols will have an additive or synergistic affect on the expression of PPARγ in colon cancer cell lines.
The combination significantly decreased the expression of Bcl-2 to ∼0.08-fold compared with a ∼0.91-fold decrease by GA or ∼0.32-fold CDDP alone, but had no affect on the expression of Bcl-XL.
DNA methylation also modulates expression of LMP2A in BL, HD, and NPC, but has no affect on the expression of major EBV oncogenic protein LMP1 (Young and Rickinson 2004).
Taken together, these results indicate that the oncogenic functions of HOTAIR may be partially exerted through its affect on the expression of HOXA5; however, further experiments are needed to elucidate the precise molecular mechanisms by which HOTAIR regulates HOXA5.
Next, we asked whether Tregs also have an affect on the expression levels of other cytokine receptors of CD4+ responder T cells and, if so, whether IL-6 and IL-1 can reverse this effect.
Taken together these results show that SMARCB1 over-expression, and HDACi drugs, have identical affects on the allelic expression of CDKN1C.
Here, we examined the question of whether or not ANT2 knockdown by shRNA affected on the VEGF expression, and if which might be regulated by PI3K/Akt signaling pathway.
In the present study, we demonstrate a novel androgen receptor-mediated mechanism leading to the activation of the DAX-1 gene transcription, which, in turn, negatively affects on aromatase expression and activity in hormone-dependent MCF-7 breast cancer cells.
