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Lis1 preferentially affects elimination of filopodia and spines, while their rates of formation are less affected during adolescence in mice (Fig 1).
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Hydraulic retention time [HRT] and sludge retention time [SRT] are known to affect elimination rates of selected pharmaceuticals.
These genetic polymorphisms could affect elimination rate.
According to results from the EU project Poseidon [ 22], adsorption processes affect elimination of diclofenac.
The factors that affect elimination rates must be taken into account when predicting past exposures and body burdens of these chemicals and when comparing current serum congener profiles to exposure media.
Therefore, the binding event affects drug elimination from the body, efficacy, duration of action and toxicity.
This small change in t1/2 suggests that CYP3A4 inhibition by ketoconazole negligibly affects the elimination of apremilast.
It is unlikely that indisulam affects renal elimination of carboplatin, because only seven out of 391 patients that had previously been treated with indisulam had renal dysfunction.
Compounds arriving at WWTPs may be eliminated from wastewater, depending mainly on their capacity to associate with particulate matter (which influences their removal by physicochemical or biological treatments) and their susceptibility to biological transformation (which certainly affects their elimination by biological treatment) (Ternes and Joss 2006).
For instance, in dogs the co-administration of ketoconazole and midazolam resulted as expected in a reduced elimination of midazolam but did not affect the elimination of fentanyl [30].
Hot compresses have no effect on ICG elimination in healthy subjects but seem to affect the elimination of ICG metabolites.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com