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A rigorous examination of how additivity to background affects dose response for different modes of action should be undertaken before its general applicability is assumed.
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Also, without access to clinical information we were unable to verify the indication for levothyroxine treatment in cohort members that affects dosing.
These differences might affect dose adjustment between the two subpopulations.
The factors that affect dose delivery in clinical fields (i.e., mechanical tolerances, motor fatigue, and latency effects) have been quantified.
CONCLUSIONS: Nitric oxide can be administered through 35 ft. of standard oxygen tubing without significantly affecting dose delivery.
Variables affecting dose given include patient weight, renal function, dose per unit weight and subsequent re-dosing schedule.
It is important to be aware of issues such as consistency of device activation and puffing as it will affect dose.
But it perfectly illustrates how multifaceted and intricately constructed "Peter and the Starcatcher" is, how its many parts combine to deliver an affecting dose of sentiment and philosophy along with plenty of fantasy and fun.
Changes in rectal and bladder fullness can affect dose distributions.
Factors affecting dose selection, such as efficacy or tolerability, were not explored in this study.
This event did not affect dose escalation because it occurred during the second cycle.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com