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The phrase "affects a number of" is correct and usable in written English.
It can be used when discussing the impact or influence of something on multiple entities or aspects.
Example: "The new policy affects a number of employees across different departments."
Alternatives: "impacts several" or "influences a variety of".
Exact(58)
"It affects a number of different neurotransmitters, and all cells can take it up".
The actual implementation of the bill would be complex as it affects a number of government ministries.
The partisan haggling over the rule affects a number of regulators.
In response to the Barcelona ruling Airbnb said: "Barcelona should stay on the cutting edge of innovation, and we're disappointed to see a ruling that affects a number of companies and that will hold the city back.
N-glycosylation is a common protein modification process, which affects a number of properties of proteins.
The seasonal transition of the boreal forest between frozen and non-frozen conditions affects a number of ecosystem processes that cycle between winter dormant and summer active states.
The seasonal transition of the land surface between frozen and nonfrozen conditions affects a number of terrestrial processes that cycle between wintertime dormant and summertime active states.
An exploit that affects a number of Netgear routers can easily give hackers access to your wireless admin password which could lead to router lock-out or, worse, illicit use of your Internet.
Due to these characteristics of the deployment chain, once any point of the deployment chain is compromised, the attack is not easily detected and affects a number of devices.
Similar(2)
This is the latest in a series of car recalls affecting a number of different companies.
"This ruling could adversely affect a number of cooperatives throughout the metropolitan area," Mr. Brett said.
More suggestions(18)
afflicts a number of
impacts a number of
affects a proportion of
reflects a number of
affects a multitude of
alters a number of
hurt a number of
engages a number of
outcomes a number of
consequences a number of
influencing a number of
impact a number of
affecting a number of
affected a number of
effect a number of
implications a number of
affects a subset of
affects a range of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com