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The phrase "affecting the validity and" is correct and usable in written English.
It can be used in contexts discussing the impact of certain actions or factors on the validity of a claim, argument, or document.
Example: "The new evidence presented in court is affecting the validity and reliability of the witness's testimony."
Alternatives: "impacting the validity of" or "influencing the validity and".
Exact(4)
"We are concerned that this pattern of publication distorts the medical literature, affecting the validity and findings of systematic reviews, the decisions of funding agencies and, ultimately, the practice of medicine," Dr. Joseph M. Heyman, a member of the A.M.A.'s board of trustees, said in a statement.
There are basic methodology and reporting practices in the laboratory study of human eating behavior that are sub-optimal and this is likely to be affecting the validity and replicability of research.
However, the level of detail is limited in this demonstration as only 5 rainfall duration scenarios are simulated for each rainfall ARI, affecting the validity and resolution of the cumulative distribution used to determine event AEP.
Small number of clusters and large variation of cluster sizes commonly exist in cluster-randomized trials (CRTs) and are often the critical factors affecting the validity and efficiency of statistical analyses.
Similar(56)
Any such modification or deletion shall not affect the validity and enforceability of the rest of these terms and conditions.
Sample size is an element of research design that significantly affects the validity and clinical relevance of the findings identified in research studies.
The formulation derived here does not involve any derivatives of material properties and moreover, it can be proved that an arbitrary interface in the integral domain does not affect the validity and the value of the interaction integral.
There are two main failures that affect the validity and reliability of SR.
If any provision is deemed to be unlawful or unenforceable, that shall not affect the validity and enforceability of the remaining provisions.
Another limitation of this study was the unavailability of sample size calculation, which may also affect the validity and reliability of the study findings.
In addition, technical reliability and usability considerations represent key conditions that affect the validity and general acceptability of tests (Ehlers et al. 2013).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com