The phrase "affecting the conformation" is correct and usable in written English.
It can be used in contexts related to science, particularly in chemistry or biology, where the shape or structure of a molecule or protein is influenced by certain factors.
Example: "The binding of the ligand is affecting the conformation of the protein, leading to a change in its activity."
Alternatives: "influencing the structure" or "modifying the shape".
The use of such dissimilar frameworks requires particular attention to antigen contact residues outside the classical CDR definition and to residues capable of indirectly affecting the conformation of the antigen binding site.
We hypothesized that when V617 is mutated to Phe, this could influence the neighboring F595, affecting the conformation of the αC helix of JH2 in a specific manner, that would promote activation in the absence of ligand (Figure 1C).
Together, these interactions may switch on ATR kinase activity by synergistically affecting the conformation of the activation loop.
If loop 3 contacts this constriction, it could affect a known structural regulator of translocation, affecting the conformation of the ribosome in a way that favors eEF2 function.
Smaller, but significant shift changes indicate that binding may alter this interface by affecting the conformation of the helix-turn-helix motif that constitutes a part of it.
It is caused by the expansion of a CAG repeat that codes for a stretch of glutamine residues, affecting the conformation and aggregation propensity of the huntingtin protein.
One obvious possibility would be that the extra-ribosomal interaction might allosterically affect the conformation of the PTC through a cascade of ribosomal conformational changes from the PTC-distal to the PTC-proximal locations of the ribosome.
Most of the AGU mutations do not hit the active site of AGA, but rather affect the conformation of the precursor and thus prevent the cleavage into subunits.
It was indicated that metal ions greatly affected the conformation and stability of the G-quadruplex.
The results of the light scattering experiments suggest that the incorporation of the hydrophobic naphthyl group dramatically affects the conformation of the parent polymer.
The relative broadness of several bands over 60°C suggests that the increased mobility of the long side chains affects the conformation of the α-helical backbone.
