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Surface properties can be controlled in this manner without affecting the bulk of the material [8, 9].
Animal models indicate that this process may appear in waves of active and passive DNA demethylation mechanisms, affecting the bulk of the genome and imprinted genes at different times.
The results of the studies conducted by Palmer and coworkers [ 14, 15] specifically point to intrauterine exposure to oestrogens as affecting the bulk of breast cancer cases that are not genetically determined, perhaps by increasing the number of mammary gland stem cells and thus the risk for malignant transformation of one of them [ 4, 6, 18].
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The cuts will affect the bulk of the more than 20,000 state schools in England which are still maintained by their local authorities, rather than the fewer than 5,000 academies which are funded directly by central government.
But Peter Panaro, Mr. Friedman's lawyer in the 1980s, who said he's convinced of his innocence, said that since Mr. Goldstein was charged in connection with only a small percentage of the allegations, his recantation, even if deemed wholly credible, would not affect the bulk of the charges.
Marijuana legalization in Uruguay will hardly affect the bulk of the hemisphere's drug trade.
Consequently, preexisting CD44highCD24low cancer stem cells were depleted by concentrations of T-DM1 that did not affect the bulk of the tumor cells.
Current treatment strategies may therefore affect the bulk of the tumor cells but leave CSCs behind, serving as a starting point for disease recurrence.
The cancer stem cell hypothesis has fundamental clinical implications, as current treatment strategies may affect the bulk of the tumor cells but leave CSCs behind, serving as a reservoir for disease recurrence and metastasis [ 9- 11].
In summary, there are two distinct types of translational regulation that occur during mitosis: " Global" translational repression that affects the bulk of mRNAs and likely occurs in a sequence- independent manner.
This suggests that AtCTF7∆B does not affect the bulk of meiotic cohesin complexes to a significant extent, but rather may alter centromeric cohesin levels, or possibly cohesin interactions with SGO1 or PATRONUS [ 55].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com