Sentence examples for affecting the apoptotic from inspiring English sources

On the other hand, mutations affecting the apoptotic pathway have been found in a number of tumours.

The treatment of highly metastatic SCCHN cells with NF-κB inhibitors reduced the in vitro cell invasion capacity of the cells without affecting the apoptotic rate.

Inhibition of actomyosin contraction through ROCK or myosin ATPase blockade reduces apoptotic body numbers formed during early apoptosis and concomitantly represses protein release without affecting the apoptotic program.

Retinal cells may have a different sensitivity to chromosomal instability, which affects the apoptotic pathways.

While the initiation of apoptosis by the receptor complex and the execution via the mitochondrial pathway constitute two parts of the machinery, several other pathways affect the apoptotic process dramatically.

Similarly, we found that CD40 ligation neither promoted annexin-V binding in resting 1321N1 astrocytes (data not shown), nor co-incubation with erythrodiol or uvaol affected the apoptotic response elicited by triterpenes in these cells.

There are studies indicating that β-elemene affects the apoptotic process in cancer cells.

In addition, Noxa levels affected the apoptotic response to general nutrient depletion (i.e. amino acids, vitamins).

We also demonstrated that RUNX2 binds to and transactivates the Bcl-2 promoter, providing a mechanism for how RUNX2 affects the apoptotic potential of the cells.

However, whether or not FZHY affected, as well as how it might affect, the apoptotic signaling in primary hepatocytes were unknown.

These genetic observations suggest that both the mutational status of PER2 S662 and the levels of PER2 protein may affect the apoptotic response to X-rays.