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Altogether, these data show that TIL have gone through a process of differentiation into effector cells, but that TCR signalling was blunted at an early level, affecting severely the Ca- and Akt-pathways, and to a lesser extent, ERK activation.
Aspergillus fumigatus arthritis is an uncommon infection, mostly observed in the setting of disseminated invasive aspergillosis affecting severely immunocompromised patients.
In the winter of 2009 the influenza A (H1N1) pandemic reached Brazil, affecting severely its southern states.
However, when the default procedure was taken for the improper uniform prior, i.e. starting values are taken from an initial IGLS run, the starting value for the variance parameter was taken too small and remained so until the MCMC sampling was stopped thereby affecting severely all parameters.
Choroidal vascular lesions of PCV are more preferable found in the posterior pole of the retina, 4 although further evidence suggests that the lesion could also be found in the peripheral retina up to 63%. 3, 5 We report a case of peripheral PCV in a male patient with advanced bilateral AMD affecting severely both foveal areas.
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"His quality of life was affected severely," said Dr Weilie Hu, a surgeon at Guangzhou General Hospital.
The creditors, the bill collectors still call, and we tell them we were affected severely, because we're still in the restricted zone.
In multi-antenna systems, the crosstalk between the different MIMO channels affects severely the system performance.
China, although a distant country, yet was affected severely by the piracy.
In addition, this process affects severely the embedded watermark and the decoder produces high error rates.
Both the enzyme loading and the dry matter content affected severely the liquefaction efficiency.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com