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13 PI was defined as 'substantial' impairment of 6 months duration (or from birth), affecting functions as per the Washington Group Questions on functional limitations in core domains.
These studies revealed important functions of muscarinic receptors modulating neuronal activity and neurotransmitter release in many brain regions, shaping neuronal plasticity, and affecting functions ranging from motor and sensory function to cognitive processes.
The anti-LRP2 autoantibodies may play pathological roles by affecting functions of LRP2 None declared.
The cellular response is likely to be complex, with changes in gene transcription and regulation of proteins affecting functions of key importance to cell fate.
These observations suggest that in addition to the major lymphangiogenic function, VEGF-C may play a role as an autocrine molecule directly affecting functions of certain cancer cells which express any of these VEGF-C-binding receptors.
Hancock et al. (2006) also reported Opi− phenotypes for the first time in mutants affecting functions such as the NuA4 histone acetyl transferase, vacuolar protein sorting, and other aspects of membrane trafficking and the UPR.
Similar(51)
IL-1α activates complex pathways in endothelial cells, dramatically affecting function.
In Dicty myosin II, Loop 2 tolerates significant sequence changes without affecting function.
Genetic drift affects functions from all metabolic categories.
The latter was done with the purpose of identifying highly affected functions.
Absence of MECP2 impairs neuronal morphology and strongly affects functions of the brain [ 9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com