Sentence examples for affecting efficacy from inspiring English sources

Therefore, an NVP-AUY922 intermittent dosing regimen gives optimal tolerability without significantly affecting efficacy.

Major factor affecting efficacy for gene therapy is gene delivery system.

Clinically, PQ-preserved ophthalmic solutions appear to reduce ocular discomfort associated with drop administration without affecting efficacy [ 26, 27].

Characterize efficacy and triglycerides over time following alitretinoin administration to assess the most appropriate dose; Evaluate factors affecting efficacy and triglycerides; and Simulate clinical trials to assess the clinical relevance of any findings and potential labeling implications.

The pyrimidine analogue 5-Fluorouracil (5FU) is often used in combination with STZ (Basu et al, 2010), but toxicity remains an issue, highlighting the need to improve tolerability without affecting efficacy.

1– 3, 5 The overall goals of the LDR analyses were to: Characterize efficacy and triglycerides over time following alitretinoin administration to assess the most appropriate dose; Evaluate factors affecting efficacy and triglycerides; and Simulate clinical trials to assess the clinical relevance of any findings and potential labeling implications.

To determine if variations in common treatments for benign paroxysmal positional vertigo (BPPV) affected efficacy.

In addition to the preclinical, clinical and post marketing challenges common to other drugs, unwanted immunogenicity is known to affect efficacy and/or safety of most biotherapeutics.

However, the nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) components may also affect efficacy.

Indeed, antidrug antibodies were detected with all four antibodies [80], but these did not seem to affect efficacy [31].

We conclude that the theoretical framework adequately explains the mechanism by which the defibrillation waveform affects efficacy for monophasic waveforms and, in at least one aspect, biphasic waveforms.