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Only the subgroups of photosystem II inhibitors (HRAC group C) were pooled into one group because they are assumed to act similarly by affecting closely related targets, e.g., different bindings sites at the same molecule [9, 32].
It has been proposed that the PD-related inclusion body pathology in the nervous system progresses in six stages, starting at the OB and the ENS and affecting closely connected neural sites [39], [40].
Also gross chromosomal alterations not affecting closely located primer binding sites will not be reflected.
Similar(57)
First, rare mating events may allow the drive to affect closely related species.
As the CpG/non-CpG assignment bias primarily affects closely related sequences, we estimated substitution rates in human and chimpanzee pairwise alignments of coding and noncoding sequence.
We were wondering whether this cell non-autonomous phenomenon only affects closely neighboring tissue or whether it acts at a longer range.
The processes affected closely correspond to defined 'hallmarks' of cancer, such as resistance to cell death, extension of replicative potential, enhancement of invasiveness, and escape from immune surveillance, among others (6, 7).
Highly selective arabinofuranosyl nucleosides, which inhibit the mitochondrial thymidine kinase (TK-2) without affecting the closely related herpes simplex virus type 1 thymidine kinase (HSV-1 TK), varicella-zoster virus thymidine kinase (VZV-TK), cytosolic thymidine kinase (TK-1) or the multifunctional Drosophila melanogaster deoxyribonucleoside kinase (Dm-dNK), have been obtained.
At our knowledge, this is the first highly specific RNAi active on KGFR without affecting the closely related FGFR2-IIIc isoform.
QTL cluster V and VII are harboring seven to eight QTLs affecting either closely or allometrically related traits.
A similar perturbing effect would be predicted for the c.305C>G and c.335C>G missense changes affecting the closely located Pro102 and Pro112 residues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com