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Discover LudwigThe phrase "affecting alternative" is not correct and does not convey a clear meaning in written English.
It may be intended to describe an alternative that has an impact or influence, but the wording is awkward and unclear.
Example: "The affecting alternative to our current strategy could lead to significant changes in our approach."
Alternatives: "impactful alternative" or "influential option".
Exact(9)
But in the work's West Coast premiere Saturday at the Warner Grand Theatre in San Pedro — a semi-staged production led by company General Director Andreas Mitisek — "The Love Potion" proved a powerfully affecting alternative to Wagner's more epic and revolutionary 1865 opera, "Tristan und Isolde". Martin's score employs a chamber orchestra consisting of just seven strings and a piano.
PPT richness influences recruitment of the polypyrimidine tract binding protein (PTB), affecting alternative splicing [50], [51].
The enrichment of these genes suggests that histone deacetylation in OPCs contributes to the suppression of genes affecting alternative cell fates.
Our results suggest that SNPs affecting alternative splicing may play an important role in breast cancer and possibly other complex genetic traits.
Six of seven A5EΔ4 splicing exons could be mapped to protein-coding gene sequences and all six CDS affecting alternative exons created a PTC.
Our results are a first demonstration of feedback regulation whereby an alteration in SMN protein levels controls expression of the protein itself by affecting alternative splicing of its pre-mRNA transcripts.
Similar(51)
de la Mata, M. et al. A slow RNA polymerase II affects alternative splicing in vivo.
We then showed that genetic variation at the NCSTN locus affected alternative splicing in human postmortem brain tissue.
The aim was to establish the AT2R gene expression in human CAKUT concerning -1332A/G polymorphism, which might affect alternative splicing.
In this report we demonstrate that decoy oligonucleotides designed against specific splicing factors can bind the splicing factor, affect alternative splicing of known targets and have biological effects in line with inhibition of their splicing activity.
Although much progress has been made in understanding different alternative splicing mechanisms on an individual transcript or gene basis, much remains to be learned including how RNA structure and/or RNA chaperones affects alternative splicing on a global transcriptome-wide level.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com