The phrase "affecting a substantial proportion" is correct and usable in written English.
You can use it when discussing the impact of an event, policy, or phenomenon on a significant part of a population or group.
Example: "The new regulations are affecting a substantial proportion of small businesses in the area."
Alternatives: "impacting a significant portion" or "influencing a large segment".
Joint injury and disease are painful and debilitating conditions affecting a substantial proportion of the population.
Affecting a substantial proportion of adults, chronic kidney disease (CKD) is considered a major risk factor for cardiovascular (CV) events.
Chronic kidney disease (CKD) is a common condition, affecting a substantial proportion of adults in the U.S. and worldwide (1).
IBS, a functional bowel disorder, is a common problem affecting a substantial proportion of the population, with point prevalence estimates ranging from 10-30% [ 2- 10].
Irritable Bowel Syndrome (IBS) is a chronic, relapsing, gastrointestinal disorder, affecting a substantial proportion of the population, with recent prevalence estimates between 10.5% and 30% [ 1- 4].
Furthermore, our results demonstrate that despite LGT affecting a substantial proportion of the Streptococcus pan-genome, many of the major groups have retained distinct core characteristics since their formation.
Second, a newly released drive will typically take dozens of generations to affect a substantial proportion of a target population, unless drive-containing organisms are released in numbers constituting a substantial fraction of the population.
In conclusion, this study suggests that drug stock-outs affect a substantial proportion of patients on cART in Abidjan, even though generic the fixed-dose recommended as first-line therapy in Côte d'Ivoire, stavudine/lamivudine/nevirapine, was always in stock.
Please see related research by Salluh et al, http://ccforum.com/content/14/6/R210 Delirium affects a substantial proportion of hospitalized patients and increases their likelihood of unfavorable outcomes.
Gestational diabetes (GDM) affects a substantial proportion of women in pregnancy and is associated with increased risk of adverse perinatal and long term outcomes.
Poor mental health, including suicidal thoughts, affects a substantial proportion of surveyed women who are up to 2 years postpartum in the Amhara region of Ethiopia.
