The phrase "affecting a large part" is correct and usable in written English.
It can be used when discussing the impact or influence of something on a significant portion of a group, area, or population.
Example: "The new policy is affecting a large part of the workforce, leading to widespread changes in job roles."
Alternatives: "impacting a significant portion" or "influencing a major segment".
2017 February - Government declares a drought affecting a large part of the country to be a national disaster.
"But out of this crisis affecting a large part of the population, a sense of 'public morality' is already building up," Hamasaki said.
Nearly 90% of diarrhea-related deaths have been attributed to unsafe or inadequate water supplies and sanitation (5 )—conditions affecting a large part of the world's population.
BANKING CRISES OF the sort that affect a large part of the world, slowing global economic growth, freezing finance and crimping international trade, are mercifully rare.
Speaking at the one-day annual summit meeting of the Shanghai Cooperation Organization, President Mahmoud Ahmadinejad of Iran said the planned defense system, to be based in Eastern Europe, was "a threat to more than one country," asserting that it would affect "a large part of Asia and S.C.O.
The last major Twitter outage that affected a large part of the service's global user base occurred on June 21 , 2012 when the service was down for around an hour and forty minutes, owing to what Twitter called a "cascading bug".
But don't submerge yourself in cold water, especially if your burn affects a large part of your body, because you don't want to lose too much body heat.
The 2011 Mw 9.0 Tohoku earthquake generated an aftershock sequence that affected a large part of northern Honshu, and has given rise to widely divergent forecasts of changes in earthquake occurrence probabilities in northern Honshu.
The 2011 Mw 9.0 Tohoku earthquake generated an earthquake sequence that affected a large part of northern Honshu, including plate boundary regions of the Okhotsk, Pacific, Philippine Sea and Eurasian plates (e.g. [1]).
Apligraf has proven to be a valuable and cost effective treatment of chronic nonhealing VLU and DFU, both conditions that affect a large part of the aging population.
Obesity is a disease that affects a large part of the population and has been associated with worse outcomes after cardiac surgery.
