Sentence examples for affected the interaction of from inspiring English sources

B56γ1 R201A mutation completely abolished the binding of the BubR1 pSer676-phosphopeptide (Table 2 and Fig. S5), likely because mutation of the semi-buried B56 Arg201 induced major local conformational changes, which in turn affected the interaction of the critical BubR1 Glu674 residue in positively charged pocket (Figs. 2 and S5).

HER2 is a well-known upstream kinase of RAF/MAPK, and, therefore, we examined whether BRACs affected the interaction of HER2 with RAF1, MEK1, ERK1/2, and JNK.

To examine whether residues I123 and L146 directly affected the interaction of Nef with CD3ζ, we performed FRET and coimmunoprecipitation analyses.

These results suggest that the oligospermine architecture not only affected the interaction of the protonated portions of the polymer with the phosphate groups of siRNA but also these different siRNA complexation behaviors also lead to different efficiencies of gene knockdown.

The effect of the mutations on TFIIH complex stability was assessed in two complementary assays, which showed that the two XP mutations most clearly linked to cancer, R683W and R601L, affected the interaction of Xpd with cTFIIH and CAK.

As position 46 directly affected the interaction of NDUFC2 protein with its mtDNA-encoded partner ND4, we aimed toward assessing the association of genotype combinations involving this SNP and mtDNA SNPs with T2DM.

The T2D-specific chromatin modification patterns might result in the aberrance of DNA methylation, which affected the expression levels of the corresponding genes or directly affected the interactions of DNA histone to regulate the expression levels of the genes.

It remains to be investigated if Nup358 association affects the interaction of aPKC with other known interacting partners.

The presence of metal ion directly affects the interaction of plasma proteins with active herbal components.

This protein corona considerably affects the interaction of the nanomaterials with biological systems.

Temperature was observed to positively affect the interaction of the protein and adsorbent.