Sentence examples for affected sir from inspiring English sources

The path analysis revealed that Hydrology factors directly affected SIR and nutrient content in sediments (Fig. 7B).

In our search for the underlying mechanism, we identified a methylation-dependent mechanism that affected Sir protein targeting and a methylation-independent mechanism that involved chromatin relocalization and the histone acetyltransferase Gcn5.

Finally, misclassification of HR status by differences in for example tissue fixation, choice of antibody, scoring method and type of assay could have affected SIRs.

Targeting of a catalytically inactive Dot1G401R protein [ 2] did not affect Sir protein binding.

The second derepression mechanism, which does not affect Sir protein binding, requires the histone H3 and H4 histone acetyltransferase Gcn5.

We conclude that Dot1-mediated methylation directly affects Sir mediated chromatin and silencing from a distance, by antagonizing Sir complex binding.

Although Dot1 affects Sir protein targeting and silencing of reporter genes, loss of Dot1 in otherwise unperturbed cells has minor effects on overall gene expression ([ 37, 38] and our unpublished gene expression profiling results).

Because the NLR is based on neutrophils and lymphocytes, it would also be affected by SIR. Although most studies have recommended a NLR cut-off value of 5 (Shimada et al, 2003; Szczepanik et al, 2011), a recent report has recommended a value of 3 (Chiang et al, 2012).

Although we found that kri-1 did not affect the SIR-2.1 protein staining pattern, it still remained possible that kri-1 and sir-2.1 function in the same pathway.

Asked if he should have visited the worst affected areas sooner, Sir Philip said: "Well I'm going up there today.

Consistent results were presented between models predicted to be least (0 4 rate) and most (all age SIR) affected by ascertainment bias.