Sentence examples for affected mutation from inspiring English sources

According to the sampling design, affected mutation carriers may be preferentially sampled.

Affected mutation carriers, especially recently diagnosed patients, showed a stronger decline in psychological well-being than unaffected mutation carriers two weeks after the DNA result [ 14].

Although speculative, the differing risk patterns for paternal age in white and African-American women may reflect differing exposures for white and African-American men at that time and place, which could have affected mutation rates.

Longitudinal changes in 5 symptomatic patients (numbers 1, 2, 3, 7, 9) and the asymptomatic mutation carrier are illustrated in Fig. 2. For affected mutation carriers, the average changes in WBV and VV were −34.1 ml/year (2.47% decrease per year) and +7.46 ml/year (11.87% increase per year), respectively.

Bond et al. (2004) analyzed 88 affected mutation carriers and found that the median age of tumor onset for those who carried GG/GT (18 years) was 9.0 years earlier than that for those carrying TT (27 years) (P = 0.031) [10.031

Brain volume and rate of atrophy now approach those of affected mutation carriers.

Others are less certain; for example, I1371V has been found in one case with a self-reported family history of PD, but without clear evidence of segregation such as an affected mutation-carrying parent (Paisán-Ruíz et al., 2005).

Genomic factors that affect mutation rate in non-coding elements.

We next investigated whether overexpression of the hPolλ W438 variant could affect mutation frequency in vivo.

This broad range suggests that differences between the fragments affect mutation incorporation.

The contributions of factors that affect mutation rates can be identified using analyses of substitution rates.