Exact(3)
Driving demands significantly affected initiation location.
Among the coding sequence variants, 87% of InDel markers affected initiation and stop codons as well as frameshift mutations.
In addition, GO enrichment in genes required for telomere maintenance suggests additional target genes and loci for further investigation, as telomerase has long been considered an attractive target for therapy in endometrial carcinoma [ 44] and more recently, a mouse model of endometrial cancer showed that telomere length affected initiation of type II carcinogenesis [ 45].
Similar(57)
To investigate accessibility as a variable affecting initiation codon usage, we developed a synthetic mRNA that initiates translation by a cap-dependent mechanism.
We suggest that recently identified processes, such as the "bystander effect", might affect initiation, promotion, and malignant conversion in different ways.
Based on its wide spectrum of mechanisms of action, topiramate may exert its effect in migraine prevention by reducing nociceptive transmission through trigeminovascular modulation, and inhibiting neuronal hyperexcitability, which affects initiation and development of CSD.
The possibility that different genetic factors affect initiation and dependence has important implications for control group selection in case control genetic association studies, and may explain some inconsistent results for drug dependence.
In the present study, we have provided new insights into how the chromosomal context surrounding DS affects initiation.
The authors suggested that such reduced stability is a universal feature of mRNAs and is more likely to affect initiation codon recognition than ribosomal recruitment.
Of particular interest here is the fact that different isopod species are also known to respond to sex ratio in terms of mating behaviour [28], [48], probably because sex ratio affects initiation of precopula [20].
Loss of BLIMP1 might therefore affect initiation of DNA demethylation.
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