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Several studies reported that multiple components of the ATR pathway such as CHK1 [ 44], HUS1 [ 45], and Claspin [ 46], or other ATR substrates, profoundly affected CFS integrity when defective.
The Nor CAPITAL study had one clear selection bias, as the study included only patients who were able to attend our research clinic; and the results can therefore not be extrapolated to the most seriously affected CFS adolescents.
The NorCAPITAL study did have one clear selection bias, as the study only included patients who were able to attend our research clinic; and the results cannot be extrapolated to the most seriously affected CFS adolescents.
On the other hand, the study only included patients who were able to attend our research clinic; and the results cannot be extrapolated to the most seriously affected CFS adolescents.
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REJECT is considered a mix of Material and Mental processes with the inherent participant encoded as Agent and the second participant as Affected (cf. Actor and Goal in Halliday and Mattiessen, 2004) but the participant roles show a priority given to the Material process.
Additionally, this level comprises relevant therapies and measures to prevent a relapse in order to strengthen the psychological and physical health of those affected, cf. among others [ 12].
The mean age of our H1N1 affected CF patients was notably lower than our total CF clinic mean age ie. 22 years (SD 3) compared with 28 years (SD 9).
We evaluated how ivacaftor treatment affected CF symptoms, functioning, and well-being, as measured by the Cystic Fibrosis Questionnaire-Revised (CFQ-R), a widely-used patient-reported outcome (PRO) measure.
Individuals affected with SLI represent a fairly heterogeneous group both in terms of the severity of their primary expressive and receptive language symptoms as well as in the extent to which additional areas (academics, peer relations) are affected (cf. Schwartz, 2009).
Both insulin insufficiency and hyperglycemia negatively affect CF lung disease.
Model iKF1028 provides researchers a framework to explore and understand the global metabolism of B. cenocepacia J2315 and its key metabolic virulence factors affecting CF patients upon infection.
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