Sentence examples for affected cells to from inspiring English sources

These observations are consistent with the possibility that increased adhesion at the cell rear might lead to an inability of affected cells to detach from their migratory substrates.

Reduced hTR levels being excluded as described above, we investigated the ability of the affected cells to express hTERT and assemble a catalytically active telomerase.

Collaboratively, these events result in cessation of polarized growth and changes in cell wall structure, which allow the affected cells to become adapted to the insult [17], [24].

The redistribution of Rom2, Rho1 and Fks1 from the bud to cell periphery upon heat stress is believed to shift cell wall synthesis activity to cell periphery, where repairing or remodeling of cell wall is required for the affected cells to withstand the insult [13], [17].

The more cell divisions, the more cells involved, and the more mutations, a fraction of which will contribute in the affected cells to positive tumor cell evolution.

A transit chain is coupled to the affected cells to account for the duration of the death process after drug action.

Prion proteins exhibit ordered, self-perpetuating aggregation and are thought to transmit from an affected cell to its progeny (124, 125).

We aimed to identify gene expression changes indicating how affected cells react to and compensate for the common biochemical defect, use gene expression data to assign patients into already defined and/or putative disease subgroups, identify candidate disease causing genes, and define potential pathogenetic mechanisms associated with the disease.

The results support abnormal compartmental Zn levels in Cln6 affected cells due to Zip7 loss and the ability of ZnII atsm) to at least partially rectify this by up-regulation of MT. As increased labile Zn can trigger neurite outgrowth [ 42], we next examined the neurite characteristics of Cln6 neurons.

For a number of mitochondrial disorders, the mutant load of the affected cells has to reach a certain cell and tissue type dependent level to show a clinical phenotype [12], and the partition of the (heteroplasmic) mt genomes during cell division is subject to mitotic segregation or a germline bottleneck [13], [14].

The results of this study indicate an irreversible loss of cell membrane integrity of macrophages exposed to ≥1 ng/ml leukotoxin, with a dose-dependent increase in affected cells correlated to the concentration of leukotoxin.