The correlations of the other traits were only minimally affected by adjustment.
With respect to the median NT-proBNP value of 91 pg/mL, higher values conferred a significant twofold increased risk of overall mortality and a threefold increased risk of CV mortality, which was only slightly affected by adjustment for traditional and new risk factors, including AER, CRP, fibrinogen, uric acid, and eGFR.
The TRs were only slightly affected by adjustment, and significant trends persisted, as indicated by the IQR TRs.
Low fetal growth was strongly associated with increased risk of MI, and the risk estimates were only modestly affected by adjustment for gestational age at birth, sociodemographics, comorbidities and family history.
Results comparing HBM cases and family controls were not materially affected by adjustment for limb length rather than height, or by further adjustment for questionnaire-assessed physical activity (data not shown).
Data indicated that there was excess risk of ASD among males who were hypoxic at birth, not materially affected by adjustment for potential confounding due to birth year and socio-economic status: OR 1.13, 95%CI: 0.96, 1.33 (MAR assumption).
This result is not materially affected by adjustment for potential confounding due to birth year and socio-economic status: adjusted OR 1.13, 95%CI: 0.96, 1.33.
Results were minimally affected by adjustment for covariates (e.g. age, race, medical comorbidity, smoking, medication count, and depression) but the association was modified (p = 0.008) and mildly attenuated by adherent use of lipid-lowering medications.
The relation to stroke risk was not affected by adjustment for covariates, including C-reactive protein (Table 3).
The relation to cardiovascular mortality risk was less affected by adjustment for covariates in the subsample than in the total sample (Table 3).
The association between 25(OH D and tPA was not strongly affected by adjustment for lifestyle factors, and a significant inverse trend was apparent after further adjustment for adiposity although the effect size was halved (Figure 2D).
