Sentence examples for affected by a mutation in the from inspiring English sources

In 2007, a small group of patients affected by a mutation in the RPE65 gene became the first to have a corrective version of the gene inserted into their retina using a virus vector.

Surprisingly, the interaction with CAK is not only affected by a mutation in the HD1 domain in the N-terminal half of XPD (where Mat1 binds), but also by mutations in the C-terminal half, in particular in the center of HD2 or towards the groove.

Possibly Wnt3a levels in the mutant are affected by a mutation in a regulatory element.

The 508th amino acid, normally lysine, is affected by a missense mutation in some people with Birt Hogg Dubé syndrome.

This presumed function of RNA Pol II, which would be compromised by the rpb2-m203 mayalson, may also be affected by mutation in the Med8-Med18-Med20 submodule.

It is likely that the largest QTL are affected by multiple mutations in the same region rather than by a single mutation.

This result confirmed that release of vesicles to the extracellular space was affected by mutation in the SEC4 gene.

First, the size of the ETR1 complex is not affected by null mutations in the other receptors, CTR1, or EIN2.

Infants affected by null mutations in the Ugt1 gene develop Crigler Najjar syndrome type I (CNSI).

The distribution of vesicular and cellular sterols was apparently not significantly affected by mutation in the SNF7 gene.

These results explain the cold-sensitive phenotype of the I707L mutation in KlenTaq1 and serve as an example of a large conformational change affected by a conservative mutation.