The phrase "affect their functioning" is correct and usable in written English.
It can be used when discussing how certain factors or conditions influence the performance or operation of a system, organization, or individual.
Example: "The lack of proper training can significantly affect their functioning in the workplace."
Alternatives: "influence their performance" or "impact their operation".
Nevertheless, there is evidence to suggest that neurons and glia mutually affect their functioning through complex, not fully explored mechanisms [ 39, 43] generating alterations in the levels of excitatory (i.e., glutamate and CGRP) and inhibitory (i.e., GABA and endocannabinoids) neurotransmitters.
"I believe the centers are doing quite well, and I don't want to affect their functioning," he explains.
It is intuitively obvious that having many attacks of severe pain, nausea and other symptoms, often binding the sufferer to bed for 1 or 2 days, may adversely affect their functioning and, thus, may lead to less social advancement.
Being the most abundant anionic phospholipid in mammalian cells, it makes the largest contribution to the interfacial contacts with membrane-binding proteins and may affect their functioning [21], [22].
This, in combination with the suggestive moderation effect of coping, suggests that individuals with psychotic symptoms may be less able to handle stressful situations and that this may affect their functioning in daily life.
Even in moderately preterm children, cognitive and emotional regulation difficulties affect their functioning at school age, and a slightly lower IQ with attention and behavioral problems are found when they are compared with term-born children [ 35, 36].
We and others demonstrated that exposure of bone marrow stromal cells to common environmental contaminants, such as polycyclic aromatic hydrocarbons (PAHs), adversely affect their function [ 26- 34].
Moreover, many of the externalized proteins are modified by cleavage, likely by activated caspases, which might easily affect their function and/or recognition.
Data about proteins include all the identifiers suitable to download the related sequences, functional domains according to InterPro [ 12], structural models from the Protein Data Bank (PDB) [ 13] and drugs available to affect their function [ 8].
Ethanol disrupts the cell membranes of neurons, mildly and temporarily, but neurons are complex and delicate, so this still affects their functioning.
Within clinical practice, the physical functioning short forms can provide the medical team with additional information about how the child's condition is affecting their functioning.
