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The phrase "affect the usability and" is correct and usable in written English.
It can be used when discussing how certain factors influence the effectiveness or ease of use of a product, system, or interface.
Example: "The design choices made during development can significantly affect the usability and overall user experience of the application."
Alternatives: "impact the usability and" or "influence the usability and".
Exact(2)
In this study, we demonstrated that when the management of medical information is closely intertwined with the physician's activity, it is necessary to perform a precise analysis of this activity in order to identify the cognitive and organizational constraints that affect the usability and acceptance of the tool.
Finally, in our study, question types indeed had a significant effect on user performance that may affect the usability and security of smartphone based authentication systems.
Similar(58)
This finding may have practical implications because a reduction of the cellulose-to-lignin-ratio in the secondary xylem due to N fertilization affects the usability and economic value of wood as feedstock for biofuel production [ 3].
These case studies were relevant not only for the evaluation of BETA but also to evaluate how different features affect the usability of the approach and the quality of the test cases and to compare the quality of the test cases generated using different coverage criteria.
Studies indicate that interaction design in ERP systems is too weak, which considerably affect the usability of the product (Singh and Wesson 2009).
It also discusses fundamental issues which affect the usability of DHMIS to support District Health System (DHS), including meeting user needs and user education in the use of information for management; and the need for integration of data from all health-providing and related organizations in the district.
In this context, it would be interesting to see if socio-cultural and multi-ethnic differences in these patients would affect the usability of this self-reported appetite rating.
This Cartesian dichotomy can be fallacious, as functionalities buried in the application's logic can sometimes affect the usability of the system.
Rather than reviewing all of graphic design, this chapter merely provides a window into aspects of design that may be particularly tricky or influential in the way they affect the usability of a Web site.
Questions with long anticipated answers can affect the usability.
The use of abbreviations in answers can affect the usability of challenge questions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com