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This kind of selection is based on the identification of genes that may affect the traits of interest.
Genetic improvement in livestock is driven by increasing the frequency of favourable alleles at loci that affect the traits of interest in populations [ 1].
The results were validated by comparing the map location of the outlier AFLPs with the map location of the major QTLs and genes that affect the traits of the domestication syndrome (Koinange et al., 1996).
Future work is needed to understand how variation in gene imprinting might affect the traits of hybrid seeds, and how it might affect the evolution of new traits in hybrid plants.
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An additional challenge in using the EMR for genomic studies is assessment of comorbidities and medications that can affect the trait of interest.
The ideal approach would be to combine only those variants that affect the trait of interest.
Higher marker densities mean that markers are in stronger linkage disequilibrium (LD) with QTL that affect the trait of interest.
On the other hand, SCPCA will lose power if SNP data is indeed under the additive model assumption for introduced risk that affect the trait of interest.
QTL mapping of genetic variation affecting, for example, resistance to summer mortality [ 22] or hybrid vigor [ 6] requires a large number of mapped molecular markers and testing for associations between marker genotypes and phenotypes to identify chromosomal regions harbouring genes that directly affect the trait of interest.
The QTL cluster of qGS5.2, qPGWC5 (qDEC5) (mk1189-mk1192) on Chr05 (Table 4 and Fig. 4) simultaneously affected the traits of CS, GW, AS, PGWC and DEC and explained a phenotypic variation of 6.388 ~ 12.378 % for each trait, suggesting some pleiotropic effect for this QTL cluster.
is The detection of sequence variations of causal genes affecting the traits of interest are now possible in humans, animals and plants [ 1].
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Justyna Jupowicz-Kozak
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