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The phrase "affect the safety of" is correct and usable in written English.
You can use it when discussing how something may influence or change the safety of a person, group, or situation.
Example: "The new regulations are designed to affect the safety of workers in hazardous environments."
Alternatives: "impact the safety of" or "influence the safety of".
Exact(60)
But officials had said that those issues typically did not affect the safety of the tunnels.
The unknown DNA could possibly affect the safety of the beans, the group said.
The manufacturers' safety engineers say these changes will not affect the safety of occupants of sport utility vehicles.
During service, engineering pipelines may suffer from corrosion, which may affect the safety of the component.
The bases on which caregivers form their opinions affect the safety of patients and the public.
Such decisions can affect the safety of, and the benefits to the users and the owner.
Skid resistance on pavement surfaces can affect the safety of road users and impact their travel efficiency.
The layoffs, the union said, would affect the safety of hospital patients, staff members and the public.
Musk hasn't yet addressed these contingencies, all of which will affect the safety of his vehicles, and Tesla declined to comment further.
The development of the latter group of photosensitizers can not only improve the antibacterial killing potency, but also very likely to affect the safety of PDI.
Microbiologists at Cornell University have found that what cattle eat can affect the safety of hamburgers, opening a whole new path to controlling food-borne illnesses.
More suggestions(16)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com