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The phrase "affect the majority of genes" is correct and usable in written English.
It can be used in discussions related to genetics, biology, or any context where the impact on a large number of genes is being described.
Example: "The new environmental factors are likely to affect the majority of genes involved in stress response."
Alternatives: "influence most genes" or "impact the bulk of genes".
Exact(2)
Earlier thought to be uncommon, splicing appears to affect the majority of genes.
We also demonstrate that Hcy-thiolactone and N-Hcy-protein, rather than Hcy, affect the majority of genes.
Similar(58)
Thus, miRNAs form a complex regulatory network affecting the majority of genes.
Our in silico results show that, in contrast to what is expected under the DDC model, regulatory subfunctionalization peaks and then decreases significantly, while neofunctionalization increases monotonically, eventually affecting the majority of genes.
This suggests that biological systems have evolved to have a high degree of robustness to mutational disruptions that can affect the majority of their genes.
The settlement won't affect the majority of these homes.
In contrast with SGLp1, where gene inactivation has affected the majority of CDSs of the prophage region, in SGLp2 only 5 out of 47 CDSs are pseudogenes, retaining a completely functional lysis gene cassette for cell adhesion and invasion together with functional genes for capside formation and DNA packaging, and genes involved in the biosynthesis of the contractile phage tail [ 64].
The fact that the majority of expressed genes experience circadian oscillation also means that oscillation affects the majority of biological pathways.
Affecting the majority of shafts.
Mutations in the gp91phox gene (CYBB on chromosome Xp21.1) cause the X-linked recessive form of the disease that affects the majority of CGD patients (∼70%).
Gingivitis affects the majority of people, and advanced periodontitis is estimated to affect 5-155-15%adults.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com