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The phrase "affect the majority of" is correct and usable in written English.
It can be used when discussing the impact or influence of something on a large group of people or things.
Example: "The new policy is expected to affect the majority of employees in the organization."
Alternatives: "impact most of" or "influence the bulk of".
Exact(36)
"The fare increase will affect the majority of transit riders in Connecticut, but not all of them," said David Lee, general manager of CT Transit.
The change of policy is unlikely to affect the majority of the nation's college applicants, since most American universities do not require SAT II tests.
By telling Joe Scarborough that Stupak isn't so bad, that it won't affect "the majority of America" – just low-income women – and that it's "an example of having to govern with moderates".
"While the changes won't affect the majority of postal users, Ofcom expects Royal Mail to communicate clearly with any affected consumers and ensure that their reasonable needs continue to be met".
Broaden the message, talk about issues which deeply affect the majority of people: for instance, ideas to give more choice for parents to get their children into a good school, to make healthcare more responsive and humane, and to make the internet safer, especially for children.
Although region locking doesn't affect the majority of gamers, among the hardcore it tends to be a sticking point.
Similar(24)
Affecting the majority of shafts.
Mycobacteriosis is an often fatal wasting disease that has affected the majority of stripers in the Chesapeake.
Danila, who was sixteen years old at the time, went on to say that such "negligence" affects the majority of the population, including his father, who had served for many years in the Interior Ministry, Russia's national police force.
Last night, Gil Viets, the airline's executive in charge of restructuring, said the bankruptcy filing was inevitable, given the combination of those circumstances, which he said had affected the majority of airlines.
While the "bedroom tax" would be scrapped, social housing would be prioritised for claimants "whose parents and grandparents were born locally", potentially affecting the majority of new local authority tenants in London and other large cities.
More suggestions(15)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com