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The phrase "affect the functioning of" is correct and usable in written English.
You can use it when discussing how one factor influences the performance or operation of another entity or system.
Example: "The new software update may affect the functioning of the existing applications on your device."
Alternatives: "influence the operation of" or "impact the performance of".
Exact(60)
Even magnets, which he says exert insufficient fields to affect the functioning of nerves, are given their due.
The same goes for how income inequality might affect the functioning of a democracy.
It's not all one way of course; apparently the stomach and digestive system can directly affect the functioning of the brain too, influencing mood and behaviour.
Nervous system disease, any of the diseases or disorders that affect the functioning of the human nervous system.
The eight B-complex vitamins function in coordination in numerous enzyme systems and metabolic pathways; thus, a deficiency of one may affect the functioning of others.
The existing regular ventilation system does not affect the functioning of the unit.
Then, the problem becomes how this lack of knowledge may affect the functioning of the system.
Species abundances directly affect the functioning of an ecosystem and its conservation value.
Environmental changes associated with urbanisation can affect the functioning of ecosystem processes.
This additional barrier could affect the functioning of anti-HIV microbicide gels and placebos.
Exposure to heavy particles can affect the functioning of the central nervous system (CNS), particularly the dopaminergic system.
More suggestions(17)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com