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In courtrooms, expert testimony about a defendant's mental disorder could affect the disposition of the case.
Bortezomib co-administration was not found to affect the disposition of gemcitabine and its metabolites.
However, there are some factors known to affect the disposition of free cortisol in plasma.
Malaria in pregnancy does not affect the disposition of parenteral artesunate.
It is well established that disease can affect the disposition of xenobiotics.
23 Comedications are also known to affect the disposition of olanzapine and clozapine.
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But gelding also affects the disposition of a horse, especially 3-year-old colts, who are akin to teenage boys raging with hormones and discovering girls for the first time.
Probably by the same mechanism, efavirenz-based HIV therapy affects the disposition of endogenous compounds, but this effect is difficult to directly link with efavirenz because it is used in combination with other drugs.
Drug intercalation critically affects the disposition of catalytic groups within the complex, tying up the active site Arg 117, pushing the reactive 3' OH and 5' phosphate DNA ends far apart (5.9 Å) and displacing Mg2+ ions by 4 Å (Figure 3A and Figure S2A).
(2155) Ionization has long been recognized as an important factor that affects the disposition of chemicals.
In the course of model development, we tested whether co-administration of bortezomib affects the disposition of gemcitabine and/or its metabolites.
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