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Multifunctional proteins in general and EMFs in particular are expected to be involved in disease since impairing their function can affect multiple cellular processes.
It has been reported to be highly active against a wide variety of tumours and to affect multiple cellular pathways.
These studies indicate that modification of anti-apoptotic genes can affect multiple cellular properties including response to apoptotic stimuli and cell growth.
The progression of lung cancer involves dynamic changes in the genome and a complex network of interactions between cancer cells with multiple, distinct cell types that form tumors. Combination therapy using different pharmaceuticals has been proven highly effective due to the ability to affect multiple cellular pathways involved in the disease progression.
Hundreds of mouse coat color mutants have been identified, covering over 100 loci, which affect multiple cellular processes [4], [5].
MicroRNAs affect multiple cellular pathways through inducing the mechanism of RNA interference at the posttranscription level.
Similar(41)
However, subsequent investigations into other actions have revealed that there may be numerous mechanisms of action affecting multiple cellular targets.
Drugs with nitro groups generate free radicals under anaerobic growth conditions, and drugs with peroxide groups generate radicals under aerobic growth conditions, both affecting multiple cellular pathways.
The SET oncoprotein participates in cancer progression by affecting multiple cellular processes, inhibiting the tumor suppressor protein phosphatase 2A (PP2and and inhibiting the metastasis suppressor nm23-H1.
As described in trauma patients [14], septic shock appears to produce a global reprogramming of the leukocyte transcriptome affecting multiple cellular and molecular functions and pathways.
Protracted low level oxidative exposure can induce accumulated cell disruption, affecting multiple cellular functions.
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