Previously it was shown that the fusion of GFP to the C-terminus of the MADS domain protein AP1 does not affect its function, as it is able to complement the ap1 mutant [ 28].
Jalan et al. [ 11] found that xopAD is upregulated in Xcaw12879 compared to strain IAPAR 306, suggesting that the IS interruption may not have completely pseudogenized this gene in Aw, although the truncation could potentially affect its function where it is present.
Guo et al. also generated a second line of mice carrying a mutation in ALK7 that does not affect its function, but renders it sensitive to inhibition by a custom-made chemical.
There could be a very small variation in the calculated and actual content of the functional group in the nanocarrier; however, we believe that it would not greatly affect its function.
The C-terminus of α-toxin is believed to bind Ca2+ ions [ 25]; the truncation found in JGS6956 Csp would likely render it unable to bind Ca2+, which may affect its function.
In some cases, these modifications still allow the gene to produce a functional protein but with slight variations that may affect its function.
Most bind to a protein and affect its function.
AID-tagging of Xrn1 did not significantly affect its function in BMV RNA2 translation (Supplementary Fig. 4).
It is concluded that BPA exposure has adverse effect on cardiac insulin signal transduction which may affect its function.
Considered altering a medical device to better meet your own needs, but had doubts about how the changes might affect its function?
Evaporation from the water surface of a reservoir can significantly affect its function of ensuring the availability and temporal stability of water supply.
