The phrase "affect its binding to" is correct and usable in written English.
It can be used in contexts discussing interactions, relationships, or influences, particularly in scientific or technical writing.
Example: "The presence of the inhibitor can affect its binding to the active site of the enzyme."
Alternatives: "influence its attachment to" or "impact its connection to".
We then wished to test whether phosphorylation of Sam68 by ERK could instead affect its binding to splice-regulatory RNA elements.
The variations in the rat NF-1 protein (compared to the human sequence) are not located within its DNA binding domain, thus they are unlikely to affect its binding to DNA.
One possibility is that PEST family phosphatase may dephosphorylate PSTPIP2 and may affect its binding to Src family kinases.
Dac-HYP has the identical amino sequence of Zenapax®, but due to expression in a different cell type and different expression system, Dac-HYP has glycosylation changes that affect its binding to Fc receptors.
Scambi et al. [ 34] investigated sera from patients with scleroderma and patients with sclerodermatous graft-versus-host disease using DIGE proteomics approach to reveal 14 differentially expressed proteins, including factor H which could affect its binding to endothelial cells.
Our in vitro study further confirm that a deletion of the full catalytic core domain of SIRT-1, which eliminated its deacetylase activity, did not affect its binding to PARP-1; however, the deletion failed to suppress skeletal muscle protein PARylation.
One mutant, ER-L372R, lost the ability to interact with CoRNR box-containing peptides without affecting its binding to LXXLL motif-containing peptides.
Both of them inhibit the LacI binding to the operator DNA without affecting its binding to non-operator sequence.
Thus, the cleavage of 11 C-terminal residues of αA-crystallin, which is known to affect its secondary and tertiary structures [16], severely affects its binding to target proteins which in turn affect its ability to function as a molecular chaperone.
Depletion of RNAs either affected its binding to cohesin or altered CTCF binding to chromatin.
Therefore, we tested whether BubR1 acetylation affected its binding to Cdc20.
