The phrase "affect genomic expression" is correct and usable in written English.
It can be used in scientific or medical contexts when discussing how certain factors influence the expression of genes.
Example: "Environmental factors can significantly affect genomic expression, leading to variations in phenotype."
Alternatives: "influence gene expression" or "impact genomic activity".
It is well established that numerous TEs are present in eukaryotic nuclear genomes and that some of them affect genomic rearrangement and gene expression via translocation [ 22].
Perturbations affect genomic regulation and gene expression is correlated across environmental and genetic variation (Proulx et al. 2007; Choi and Kim 2009; Lehner 2010b).
The expression of histone genes is co-ordinately regulated and finely balanced with DNA replication and disturbing this balance can severely affect genomic stability and gene expression by inducing DNA damage and replication fork collapse [ 1, 2].
Finally, analysis of different passages of the same tumor showed that sequential mouse-to-mouse tumor grafts did not affect genomic rearrangements or gene expression profiles, suggesting genetic stability of these models over time.
Secondly, an epigenetic mark must specifically function to control gene expression or affect genomic integrity.
Studies in this direction may provide valuable insight regarding the epigenetic status, which affects genomic conformation and gene expression.
This mitoCas9 could be applied to edit mtDNA together with gRNA expression vectors without affecting genomic DNA.
Repetitive elements comprise ~45% of mammalian genomes and are increasingly known to impact genomic function by contributing to the genomic architecture, by direct regulation of gene expression and by affecting genomic size, diversity and evolution.
Repetitive elements comprise ~45% [ 1] of mammalian genomes and are increasingly known to impact genomic function by contributing to the genomic architecture, by direct regulation of gene expression [ 2, 3] and by affecting genomic size, diversity and evolution [ 4- 8].
