Sentence examples for affect genome expression from inspiring English sources

peruviana and reveal how tandem gene arrays and CNV affect genome expression.

Epigenetic marks affect genome expression and genotype-phenotype relationships in general.

Thus, changes in PABPN1 levels could directly affect genome-wide expression profiles.

The key question is whether this epigenetic differentiation of populations is associated with adaptive genetic divergence, because unlike the natural DNA sequence variation-based markers, methylation-based variation might affect genome function by altering gene expression.

All these recent outcomes reveal important genome dynamics, which affect genome size or organization and alter gene expression.

As development is highly dynamic throughout gestation, we asked how alcohol exposure might affect genome-wide gene expression at the critical stage of neurulation (E8-10), when the nervous system (and other major organs) are actively forming in mouse.

To determine whether this altered chromatin state was sufficient to affect genome-wide gene expression, and whether TERT would prevent these changes, we performed a microarray analysis on primary and TERT+ cells expressing either lamin A or progerin at 4 weeks after induction.

Cohesins mediate sister chromatid cohesion and cellular long-distance chromatin interactions affecting genome maintenance and gene expression.

Thus, identifying the epigenetic mechanisms by which RT inhibition affects genome-wide gene expression may help us to understand the crosstalk between RT and the pathogenesis of breast cancer.

Hypoxia is a major characteristic of solid tumors and a condition that affects genome-wide changes in gene expression, which greatly impacts cellular and tumor tissue physiology particularly respiration and metabolism [23] [29].

We discuss these findings in light of the role of KV10.1 in cancer, as the INM has been shown to affect gene expression, genome stability and cell senescence, all of which are relevant to cancer [30].