The phrase "affect distant" is not correct and does not convey a clear meaning in written English.
It seems to be an incomplete or incorrect expression, and without additional context, it is difficult to determine its intended use.
Example: "The changes in policy may affect distant communities in unforeseen ways."
Alternatives: "impact remote" or "influence far-off".
Thus, in T2DM, elevated amounts of heparanase are found in the circulation, spread systemically and may affect distant organs, tissues, and cells.
Formally, we cannot exclude the possibility that insertions affect (distant) regulatory elements situated in cis to protein-coding genes, especially when the CISs occur relatively close to genes, e.g., in HOX clusters (Fig. 1c).
Mbnl1−/− mice were analysed in two groups, data shown excludes individual mice that showed >10% thigmotaxis at the end of training as these mice may have visual complications that affect distant vision.
Depending on the modification of the regulatory landscape of specific genes, it has been shown that CNVs can affect distant transcripts in cis or in trans, and even result in a negative correlation between expression and copy number (more copies, less expression) [38].
However, the mechanisms by which the local traumatic injuries affect distant organs remain unknown.
However, despite these attractive speculations on the genes vicinal to the associated SNPs, it is possible that these variants may also affect distant as yet unidentified target genes.
Each morning, bands of children pose by stone-paved roads affecting distant and beautiful gazes.
Large volcanic eruptions may lead to significant tephra dispersion, crossing borders and affecting distant and industrial societies in various ways.
These tsunamis had a major impact on public consciousness as they made their way across the oceans, affecting distant islands and coasts up to 24 hours after the earthquake.
Importantly, elevated levels of heparanase were also found in the plasma of diabetes patients (Fig. 1C, D), ultimately leading to systemic spread of heparanase, possibly affecting distant organs, tissues and cells.
We show that plasticity-induction in a given connection also affects distant pathways.
