Sentence examples for affect different steps of from inspiring English sources
Aberrant expression of mRNA binding proteins affect different steps of mRNA metabolism, significantly altering gene expression.
We further demonstrate that these proteins can affect different steps of the metastatic cascade: LTBP3 and SNED1 appear to promote early stages of invasion and dissemination, whereas EGLN1 and S100A2 act at later stages of the metastatic cascade.
Exposures in the real world do not occur to single substances but to mixtures of toxicants that can interact with each other or affect different steps of multistage disease processes.
It is logical to assume that a combination of dobutamine and levosimendan would augment their respective inotropic effect because they affect different steps of the cardiac myocyte calcium metabolism [ 35, 36].
This class of proteases affects different steps of the coagulation cascade, often nonspecifically, by proteolytic degradation.
To investigate this crucial issue we have demonstrated, by using different approaches, that lamin B1 dysregulation affects different steps of gene expression, namely transcription and alternative splicing.
Mutants have been identified that affect different steps in PGC formation and behavior.
Resistance to a first inhibitor of an enzyme and hyper-susceptibility to a second inhibitor of the enzyme generally is understood to indicate that the two inhibitors affect different reaction steps of the enzyme and/or bind to and stabilize different conformational states of the enzyme (Tachedjian et al., 1996; Selmi et al., 2003).
We isolated and characterized 11 non-toxic mutants of Cry1Ab toxin affected in different steps of the mechanism of action namely binding to receptors, oligomerization and pore-formation.
We isolated and characterized Cry1Ab mutants affected at different steps of their mode of action, namely receptor binding, oligomerization and pore-formation to determine if any of them showed a DN phenotype.
SNPs can span in the entire region of the pri-miR affecting the different steps of microRNA processing or the pairing with the 3′UTR of target genes.
