The phrase "affect a large fraction" is correct and usable in written English.
It can be used when discussing the impact or influence of something on a significant portion of a population or group.
Example: "The new policy is expected to affect a large fraction of the workforce, leading to changes in job roles and responsibilities."
Alternatives: "impact a significant portion" or "influence a considerable share".
Directly transferred to a road situation, these results indicate that salt in much smaller amounts than what is currently used could weaken snow considerably, provided that the solution is sufficiently distributed to affect a large fraction of the grain bonds.
The bottom line is that in places like that, in Namibia for sure and to some degree in South Africa and Swaziland and Zimbabwe, new infections are decreasing very dramatically, much more so than in the U.S. One of the reasons is probably because they're generalized epidemics that affect a large fraction of adults.
Both diseases affect a large fraction of the world population, with prostate cancer affecting one in six men, and CFS affecting an estimated 0.4 to 1% of the population.
The analysis combined a number of data sets to show that compliance with a range of alternative annual and 24-hr PM2.5 standard groupings would affect a large fraction of the total population in the Northeast.
"The Knowledge Graph features affect a larger fraction of queries than Universal Search.
From left to right (total, urban, agricultural part of the catchment) the exposure profiles affect a larger fraction of combinations of species and effect type and more severe effects are seen earlier.
We propose a research agenda to fill knowledge gaps and catalyze a conversation about an approach to wildlife management that affects a large fraction of public and private land.
Induction of APECs is rapid and affects a large fraction of cells.
Past this threshold, cascades start affecting a large fraction of the network, resilience collapses and the fitness declines rapidly.
It has been shown previously that exposure through incorporation of contaminated food potentially affects a large fraction of the population and poses the most relevant radiological risks once evacuation measures have been completed.
Within each genome compartment, weak selection affects a larger fraction of indels than of SNPs, and, among indels, a larger fraction of deletions than of insertions.
